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Figure 3

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Publication: Yehuda et al., 2023 - Inversely Regulated Inflammation-Related Processes Mediate Anxiety-Obesity Links in Zebrafish Larvae and Adults
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Figure 3

Most differentially expressed (DE) long intergenic noncoding RNAs (lincRNAs) were upregulated in the anxiety model and downregulated in the obesity model, similar to protein-coding genes. (A) Long noncoding RNAs (lncRNAs), classified as long intergenic noncoding RNAs (lincRNA) (purple), processed transcripts (dark grey), and retained introns (light grey) with fold change > 1.5 or <0.66, FDR < 0.05. Arrows pointing upward: upregulation, arrows pointing downward: downregulation. Yellow: obesity model; red: anxiety model. (B) qRT-PCR of lincRNA. N = 5–8 replicates (10–30 larvae/replicate), 2–3 separate experiments. Reference genes: average of eef1a1l1 and actb2. *—p < 0.05, **—p < 0.01, ***—p < 0.001. Student’s t-test.

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