Figure 5
Expression of klhl genes in response to herpesvirus infection. (A) Heatmaps depicting expression of klhl genes in three C. gibelio clones before and after CaHV-2 infection. Differentially expressed genes with upregulated and downregulated expression levels after CaHV-2 infection are indicated by red and blue circles, respectively. C: Head–kidney tissues from healthy fishes. D: Head–kidney tissues from infected fishes. (B) Pearson correlation coefficients (r) for expression changes of DEGs among three clones. (C,D) Expression verification of keap1a-A (C) and klhl12-B (D) by qPCR. Data are presented by mean ± sd. ns.: no significance; * p < 0.05.