ZFIN Image: Vicente et al., 2022, Fig. 6

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Figure Caption

Fig. 6 Cardiac Ca²⁺ handling and contractility in NAC-treated sibling and Tg-plnb^R9C 9 dpf zebrafish larvae expressing mCyRFP1-GCaMP6f. A) Ratiometric images from beating hearts, with their corresponding ventricular Ca²⁺ traces from representative control and NAC-treated sibling and Tg-plnb^R9C larvae. B) Diagram of the ventricular diameter (?m) vs. ventricular Ca²⁺ levels (ratio) from representative control and NAC-treated sibling and Tg-plnb^R9C larvae. C) HR, ventricular CaT amplitude, relaxation velocity, FS, FAC, ESV, EDV and SV from control and NAC-treated sibling (n = 23 and n = 21, respectively), and control and NAC-treated Tg-plnb^R9C (n = 29 and n = 27, respectively) zebrafish larvae. Statistical analysis was performed using a one-way ANOVA test with Tukey's multiple comparisons post-test. Data are shown as mean � SD, (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001).

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Reprinted from Journal of Molecular and Cellular Cardiology, 173, Vicente, M., Salgado-Almario, J., Valiente-Gabioud, A.A., Collins, M.M., Vincent, P., Domingo, B., Llopis, J., Early calcium and cardiac contraction defects in a model of phospholamban R9C mutation in zebrafish, 127-140, Copyright (2022) with permission from Elsevier. Full text @ J. Mol. Cell. Cardiol.