ZFIN Image: Vicente et al., 2022, Fig. 3

Image

Figure Caption

Fig. 3 Atrial and ventricular contractility and hemodynamics in sibling, Tg-plnb^wt and Tg-plnb^R9C 3 dpf zebrafish larvae expressing mCyRFP1-GCaMP6f. Fractional area change (FAC) for the atrium (A) and the ventricle (B) from sibling (n = 23 for A and 30 for B), Tg-plnb^wt (n = 18 for A and 24 for B) and Tg-plnb^R9C (n = 19 for A and 32 for B) zebrafish larvae. Heart rate (HR), relaxation velocity and relaxation time 90%–10% for the atrium (A) and the ventricle (B) from sibling (n = 13 for A and 30 for B), Tg-plnb^wt (n = 12 for A and 24 for B) and Tg-plnb^R9C (n = 15 for A and 32 for B) zebrafish larvae. C) Ventricular function parameters: EDV, ESV, SV, EF, and CO in sibling (n = 30), Tg-plnb^wt (n = 24) and Tg-plnb^R9C (n = 32) zebrafish larvae. Statistical analysis was performed using a one-way ANOVA test with Tukey's multiple comparisons post-test. Data are shown as mean ± SD, (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001).

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Journal of Molecular and Cellular Cardiology, 173, Vicente, M., Salgado-Almario, J., Valiente-Gabioud, A.A., Collins, M.M., Vincent, P., Domingo, B., Llopis, J., Early calcium and cardiac contraction defects in a model of phospholamban R9C mutation in zebrafish, 127-140, Copyright (2022) with permission from Elsevier. Full text @ J. Mol. Cell. Cardiol.