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Fig. 4
Quantification of apoptotic index of A2780 cells. (A) Western blot for quantification of BAX, BCL-2 and β-actin in A2780 cells after 48 h incubation with IC50 of JHOR11, 0.1 μM Doxorubicin as positive control or 0.1% (v/v) DMSO (control). (B) BAX and BCL-2 protein expression after normalization to respective β-actin and control. The value of the control is represented as a dotted line. (C) Apoptotic index calculated by BAX/BCL-2 ratio. The value of the control is 1, represented as a dotted line. Bars represent the average ± SD of three independent experiments. * p value < 0.05 relative to control.
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