ZFIN Image: Tang et al., 2023, Fig. 3

Image

Figure Caption

Fig. 3

Whole-genome sequencing identification of amino acid substitution P20S in SMARCE1 on chromosome 4, associated with skin color differences. A, B Manhattan plot showing a single region on Chr04, significantly associated with color differences between morphs. Red dash indicates Bonferroni-corrected critical p-value (−log₁₀(p) = 8.4). C Association signals of GWAS analysis and genetic differentiation (Fst) in significant signal region. D Gene models within significant signal region. E Maximum-likelihood tree constructed by SNPs within significant signal region. F Correlations between Ahaetulla prasina skin color phenotypes and genotypes of SMARCE1 p.P20S. G Schematic and partial alignment of SMARCE1 showing location of P20S in an evolutionarily conserved region within a proline-rich structure across vertebrates

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Genome Biol.