Figure 6
AgRP neuron ablation results in the inhibition of somatic growth and adipocyte formation. (A) Lateral view of MTZ-treated WT and AgRP4.7NTR larvae at 8 dpf. Scale bar: 500 µm. (B) Statistics of body length measurement between MTZ-treated WT and AgRP4.7NTR larvae at 8 dpf. All values are reported as mean ± SEM, n = 30. *** p < 0.001. (C) Lipid droplet accumulation was observed via whole-body Oil Red O staining of MTZ-treated WT and AgRP4.7NTR larvae at 21 dpf. Scale bar: 1 mm. (D) Left: Distribution of lipid droplets in MTZ-treated WT and AgRP4.7NTR larvae at 21 dpf, n = 30. Right: Intensity grading diagram.