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Fig. 1
Fig. 1. The experimental workflow chart. Larvae at 24 hpf were co-exposed to MPTP and three different concentrations of YIAEDAER from 24 hpf to 72 hpf, 96 hpf or 120 hpf. At 72 hpf we evaluated expression of α-syn levels. At 96 hpf we evaluated DA neurons and neural vasculature in zebrafish larvae. At 120 hpf co-treated zebrafish were subjected to regular locomotion, response to stimuli, ROS generation detection and performed for autophagy and oxidative stress-related genes expression.
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