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Fig. 4 Expression analysis by RT-PCR of OTX and p53 family genes. (A) otx1 and otx2 were found upregulated in the first 2 weeks of treatment (otx1: T1D1 vs T1D2, p < 0.01; T2D1 vs T2D2, p < 0.001; otx2: T1D1 vs T1D2, p < 0.01; T2D1 vs T2D2, p < 0.001). (B) tp53 was found upregulated in treated fish at T2 only (tp53: T2D1 vs T2D2, p < 0.01), but tp63 and tp73 at T2 and T4 (tp63: T2D1 vs T2D2, p < 0.001; T4D1 vs T4D2, p < 0.001; tp73: T2D1 vs T2D2, p < 0.05; T4D1 vs T4D2, p < 0.001). *=p<0,05 ; **=p<0,01 ; ***=p<0,001
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Full text @ Int. J. Exp. Pathol.