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Fig. 2
Transcriptome-wide association study of amyotrophic lateral sclerosis.
Manhattan plot of ALS transcriptome-wide association study (TWAS) using gene expression from the GTEx consortium brain tissues. The y-axis corresponds to two-tailed −log10 (P-values); the x-axis corresponds to genomic coordinates (GRCh37). The horizontal dashed line reflects the threshold for calling genome-wide significant genes (P = 5 × 10−6) after Bonferroni correction.
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