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Fig. 9
EOPF promoted angiogenesis by increasing p-ERK/ERK and Bcl-2/Bax expression ratios. (A) The protein levels of p-ERK (Thr202/Tyr204), ERK, and β-actin were examined by Western blot. (B) EOPF increased the ratio of p-ERK/ERK. (C) The protein levels of Bcl-2, Bax, and β-actin were measured via Western blot. (D) EOPF increased Bcl-2 expression levels. (E) EOPF decreased Bax expression levels. (F) EOPF increased the ratio of Bcl-2/Bax. Results are presented as the mean ± SD for three individual experiments. ##P < 0.01 vs untreated control, **P < 0.01 vs sunitinib.
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