ZFIN Image: Brandt et al., 2021, Fig. 1

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Fig. 1

Ablation of macrophages in WT zebrafish did not significantly impact emmetropization. (A) Representative SD-OCT B-scans from the center of mpeg1:NTR-eYFP⁺ eyes and their WT cousins with or without MTZ treatment. (B) Axial length, lens diameter, retinal radius, and body length of mpeg1:NTR-eYFP⁺ fish and their WT cousins with or without MTZ treatment. (C) Axial length normalized to body length and lens diameter. (D) Relative refractive error. Two-way ANOVA was used for statistical analysis for (B) to (D). P values are shown from Tukey's multiple comparisons for post hoc analysis. Red bars indicate statistical significance likely due to mpeg1⁺ cell ablation. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001, ^****P < 0.0001. For mpeg1:NTR-eYFP⁺ untreated, n = 11; for mpeg1:NTR-eYFP⁺ MTZ treated, n = 7; for WT cousins untreated, n = 13; for WT cousins MTZ treated, n = 9.

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Acknowledgments

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