ZFIN Image: Chen et al., 2022, Figure 5

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Figure Caption

Figure 5 GO and KEGG enrichment analysis of differentially expressed genes (DEGs) in zebrafish liver in control and HD groups. (A) GO enrichment analysis of DEGs. After redundant terms are removed from each category, only the top eight terms in p-value are displayed. (B) KEGG enrichment analysis of DEGs. Red area represents the proportion of upregulated genes in the pathway, and green area represents the proportion of downregulated genes in the pathway. Only the top 15 pathways with p-value are shown, and the ordinate order is from largest to smallest according to the proportion of upregulated genes in the pathways. (C) Heat map of expression levels of DEGs involved in fatty acid synthesis and oxidation. The key genes related to fatty acid synthesis were upregulated, such as fasn, acaca, and acacb, while the key genes related to fatty acid oxidation were downregulated, such as acox1, cpt1ab, and cpt2.

Acknowledgments

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