ZFIN Image: Chen et al., 2022, Figure 7

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Figure 7

In vitro cytotoxicity and hemolytic activity and the in vivo effectiveness of Sp-LECin. The cytotoxicity of Sp-LECin on crab hemocytes (A), human embryonic kidney cells (HEK-293T) (B), human hepatic cells (L02) (C), and mouse embryonic fibroblast (3T3) (D), were determined by the MTS-PMS assay. (E) Hemolytic activity of Sp-LECin against mouse red blood cells. Significant difference between the control group and the Sp-LECin treatment group was indicated by asterisks as * p < 0.05 and ** p < 0.01. The bars indicated the mean � standard error of mean (n = 3). (F) In vivo effectiveness of Sp-LECin in P. aeruginosa-challenged zebrafish (n = 20/group). The survival curve of each group was analyzed using the log-rank test.

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Acknowledgments

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