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Fig 5
Histological analysis of activin βA mutant females during post-pubertal maturation (55–80 dpf).
Follicles from control and βA single mutants (inhbaa-/-, inhbab-/-) showed normal growth and development. In the double mutant (inhbaa-/-;inhbab-/-), abnormal follicles with hypertrophic granulosa cells could often be observed (arrow). The boxed areas are shown at higher magnification below. The numbers shown in the photos indicate the total number of fish examined (lower) and the fish exhibiting similar phenotype to that shown (upper). PG, primary growth; PV, previtellogenic; EV, early vitellogenic; MV, mid-vitellogenic; LV, late vitellogenic; FG, full-grown.
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