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Publication: Ursu et al., 2022 - Glomerular Endothelial Cell-Derived miR-200c Impairs Glomerular Homeostasis by Targeting Podocyte VEGF-A
All Figures: Figures for Ursu et al., 2022

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Figure 1

miR-200c is upregulated in urine from patients with MGN, MCD and FSGS. (a) Fold change in urinary miR-200c expression normalized to urine creatinine and cel-39 in different renal diseases. N = 27 different patients. * p < 0.05, *** p < 0.001 compared to control. CTRL: control, MGN: membranous glomerulonephritis, MCD: minimal change disease, IgAN: IgA nephropathy, DN: diabetic nephropathy, ANCA: antineutrophil cytoplasmic autoantibody vasculitis, HUS: hemolytic uremic syndrome, FSGS: focal segmental glomerulosclerosis, PREE: preeclampsia. (b) Sequence of human (hsa) and zebrafish (dre) miR-200c. Differences are highlighted in red. The seed region of the miRs are underlined and labeled in green.

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