ZFIN Image: Burgoyne et al., 2022, Figure 5

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Figure Caption

Figure 5

Age-related changes in mitochondrial size in zebrafish are not replicated in developing mouse retinas. (A–C) There is little difference between the mitochondria within the RPE at (A) embryonic day 14 (E14) compared to a (B) postnatal day 13 (P13) and (C) 6 month old mouse (D–F) By E14, mouse retina is still developing and photoreceptors do not have fully formed outer segments (POS). At P13, the mouse has photoreceptors with almost fully developed POS. (G–I) There is a clear difference in the photoreceptor inner segment mitochondria. (G) The mitochondria are smaller at E14 compared to (H) P13 and (I) 6 month old mouse. At P13, the appearance of the (B) RPE and (E, H) photoreceptors are similar to (C,F,I) at 6 months in adult mice. Scale bars (A–I) 1 μm.

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