ZFIN Image: Wei et al., 2022, Fig. 2

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Fig. 2

Assessment of bepridil effects on zebrafish embryonic development. (a) Graphical model of in vivo bepridil treatment on zebrafish embryos. (b–g’’’’) The zebrafish embryos and larvae cultured in different concentrations of bepridil at 24, 48, 72, 96 and 120 hpf. 3000 ng/mL bepridil treatment resulted in 100% death at 96 and 120 hpf. N = 15 per group. (h) The mortality of zebrafish exposed to different concentrations of bepridil. LC₀ = 750.53 ng/mL. LC₁₀ = 1295.37 ng/mL. LC₅₀ = 2123.59 ng/mL. N = 45. (i) Correlationship and zebrafish hatchability of different bepridil concentrations at 72, 96, and 120 hpf. N = 45. (j) Correlationship and zebrafish mortality of different bepridil concentrations at 72, 96 and 120 hpf. N = 45

Acknowledgments

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