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Figure 5 Tissue comparisons between WT and p66Shc hypomorphic allele zebrafish. (A) Representative H&E stains of WT and hypomorphic allele zebrafish organs. Organs do not show tissue-level abnormalities. (B) Physical activity is not affected in the p66Shc−/+ (HA) zebrafish line, but tissue ROS levels are significantly reduced. N = 8 for physical activity, 3–4 for tissue ROS. ** = p < 0.01, mean ± SD. Both images were uniformly contrast- and brightness-enhanced for clear visualization.
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Full text @ J Cardiovasc Dev Dis