ZFIN Image: Greco et al., 2022, Figure 3

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Figure Caption

Figure 3 Characterization of EVs cargo. (A) Gene ontology enrichment analysis relative to proteins with a significantly higher expression in VSMC^PCSK9-EVs. (B) Volcano plot of miRNA with a significantly different expression between VSMC^PCSK9-EVs and VSMC^WT-EVs. (C) Venn diagram of miRNAs targets. All predicted genes for the differentially expressed miRNAs were filtered according to their relationship with atherosclerosis and inflammation and were selected for checking gene targets overlap. Results show t miRNAs target common genes. EVs, extracellular vesicles; VSMC^PCSK9-EVs, EVs released by VSMCs overexpressing PCSK9; VSMC^WT-EVs, EVs released by VSMCs wildtype.

Acknowledgments

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