Fig. 6
foxc1a?CED1?3 mutant embryos display defects in the developing superficial choroidal vasculature. A?C? Three-dimensional maximum intensity projection images of the ocular vasculature in live control (A?C) or foxc1a?CED1?3 homozygous (A??C?) embryos carrying fli1a:EGFP transgene at 3-, 5- and 8-dpf. Mutant embryos show abnormal development of the dorsal and nasal radial vessels (orange arrowheads in A??C?), enlarged and deformed superficial annular vessel (orange arrows) and a highly disorganized vasculogenesis in the ventral part of the eye with no visible ventral radial vessel at 5- and 8-dpf (orange asterisks). DRV (dorsal radial), NRV (nasal radial), SAV (superficial annular), and VRV (ventral radial) blood vessels are indicated