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FIGURE 1
Verapamil-induced heart failure model in zebrafish (A) Experimental scheme for heart failure model in zebrafish. (B) Representative images of vehicle-treated and verapamil-treated zebrafish heart. The heart of ES was shown in red line, and the heart of ED was shown in yellow line; ES: end systole, ED: end diastole (C?H) Quantification of cardiac function in Tg(cmlc2: eGFP) zebrafish larvae with verapamil. HR: heart rate, FAC: fractional area change, SV: stroke volume, FS: fractional shortening, EF: ejection fraction, CO: cardiac output. N ? 20. # p < 0.05 vs. Control, ## p < 0.01 vs. Control.
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