Fig. 6
Fig. 6. L72 triggers apoptosis by attenuating angiogenesis in zebrafishes. (A) Intersegmental angiogenesis of transgenic zebrafish 72 hpf embryos exposed to different concentrations of L72. (B) Embryo and larva mortality rate of transgenic zebrafish exposed to different concentrations of L72. (C) Larval malformation rate of transgenic zebrafish exposed to different concentrations of L72. (D) Embryo heart rate of transgenic zebrafish exposed to different concentrations of L72. (E,F) Embryo hatching rate of transgenic zebrafish exposed to different concentrations of L72 at 48 hpf (E) and 72 hpf (F). (G?I) Relative expression of genes, Flk-1 (G), EGFP (H) and STAT3 (I) treated with 4.8 µM of L72 on 24 hpf transgenic zebrafish. **p < 0.01, ***p < 0.001, ****p < 0.0001, versus blank.