Fig. 6
Investigation of Doc2a down-regulation promoting hyperplastic nerve fibers in zebrafish intestinal tract. (A–D) Comparison of enteric nerve fibers (Tubulin) in different groups. (E–H) Comparison of enteric neurons (HuC/D) in different groups. Red arrow, enteric nerve fiber; yellow arrowhead, enteric neuron. (I) Diagram of zebrafish. (J) Comparison of average number of enteric neurons in zone 1 and 2. (K) Comparison of length proportion of intestinal tract with hyperplastic nerve fibers in zone 1 and 2. #, p > 0.05; ***, p < 0.001, one-way ANOVA with Bonferroni post hoc, n = 3. Abbreviations: MO, Morpholino; ret, ret proto-oncogene.