ZFIN Image: Risato et al., 2022, FIGURE 3

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Figure Caption

FIGURE 3

Long-term hypoxia induces cardiovascular modifications in zebrafish embryos/larvae. (A–D) After a 5-days incubation in 5% hypoxia, 6-dpf zebrafish larvae display enlarged heart and inflated myocardial layer, as evidenced by the fluorescence of the myocardial transgene Tg(tg:EGFP-myl7:EGFP)^ia300. (E,F) After a 2-days incubation in 5% hypoxia, 3-dpf zebrafish embryos display disorganized intersegmental vessels (arrows), identified by the endothelial transgene Tg(fli1:EGFP)^y1. 6-dpf larvae and 3-dpf embryos are in lateral view, anterior to the left. Sample size: n = 10; ** = p < 0.01; *** = p < 0.001; R.I. = Relative Intensity; R.D. = Relative Diameter. Test: Unpaired t-test.

Acknowledgments

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