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Fig. 6
Systole vs diastole circularity analysis
(A) Inner curvature nuclei are observed to have a circular shape, (symmetric circle elongation = 1, ellipse <1) with slightly higher values observed for the diastole.
(B) Outer curvature cardiomyocyte nuclei are observed to have an elongated shape with higher elongation observed in the diastole.
(C and D) Volumetric reconstructions of the circular shape of inner curvature and elliptic shape of outer curvature myocytes were visually presented, respectively. In addition, the corresponding lateral and axial views are shown with binary images (scale bar = 15 um).
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