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- ZDB-IMAGE-220809-35
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- Serifi et al., 2021 - Targeting of SET/I2PP2A oncoprotein inhibits Gli1 transcription revealing a new modulator of Hedgehog signaling
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Fig. 1-Supp Hh signaling is reduced in Tg12x_Gli transgenic zebrafish embryos injected with seta/b morpholino (MOab).
One- to two-cell stage Tg12x_Gli transgenic zebrafish embryos were injected with 7.5 ng of seta/b translation blocking morpholino (MOab) and examined under a confocal fluorescence microscope (n=62). The squares show enlargement of the trunk areas which display decreased mCherry fluorescence intensity. Note the disrupted morphology of the somites in the marked regions.
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