ZFIN Image: Woli?ska-Nizio? et al., 2022, Fig. 4

Image

Figure Caption

Fig. 4

Deficiency of Tollip does not worsen the phenotypic hallmarks of Gaucher disease in the zebrafish model. (A) The general phenotype of zebrafish adults (3?mpf) of the examined mutant genotypes (tollip ^+/+/gba1 ^?/?; tollip ^?/?/gba1 ^+/+; tollip ^?/?/gba1 ^?/?), compared to the wild?type genotype (tollip ^+/+/gba1 ^+/+). Scale bar 1?cm. (B) Swimming velocity examined in the mutant and wild?type lines. Data are averaged within the tested groups, triangles indicate individual fish (n?=?8 for the tollip ^+/+/gba1 ^+/+, tollip ^+/+/gba1 ^?/?, tollip ^?/?/gba1^+/+/ groups, n?=?10 for the tollip ^?/?/gba1 ^?/? group) and the error bars represent SEM. t?test, ns.?nonsignificant, **P?<?0.005, ***P?<?0.001.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ FEBS Open Bio