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Gessler et al., 2022 - Control of Directed Cell Migration after Tubular Cell Injury by Nucleotide Signaling

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Figure 1

The involvement of adenosine receptors in zebrafish pronephros repair. (A) In situ hybridization revealed upregulation of zebrafish adora1a and adora1b after a laser-induced injury. Images were obtained two hours after the injury. (B) Depletion of zebrafish adora1a or adora1b by splice- (SBM) or translation- (TBM) blocking morpholino oligonucleotides (MO) delayed the repair process. (C) In situ hybridization revealed upregulation of zebrafish adora2aa and adora2ab after a laser-induced injury. Images were obtained two hours after the injury. (D) Depletion of zebrafish adora2aa or adora2ab by SBM delayed the repair process (mean ± SEM; 2-way ANOVA).

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This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.