ZFIN Image: Chen et al., 2022, Fig. 5

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Figure Caption

Fig. 5

N4-MSN₅₀@PEG/THPMP-mediated doxorubicin (Dox) delivery against the U87-MG cells and their stability. (A) Schematic representation of Dox loading strategy and the loading capacity. Stability assay of N4-MSN₅₀@PEG/THPMP/Dox by using (B) hydrodynamic diameter distributions and (C) zeta potential measurements in water at day 1, 8, and 15. (D) In vitro release profiles of Dox in PBS buffer (pH 7.4 and 5.5) at a physiological temperature (37°C). (E) In vitro cytotoxicity of U87-MG cells treated with different concentrations of free Dox or Dox-loaded N4-MSN₅₀@PEG/THPMP (equivalent dose of Dox) for 24 h ***p < 0.001.

Acknowledgments

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