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Fig. 3
Physical characterizations and cytotoxicity of four different negatively charged RITC-conjugated mesoporous silica nanoparticles (RMSNs) with different sizes (50 and 200 nm). (A) TEM images. Scale bar = 50 nm. (B) DLS and (C) zeta potential measurements. (D) Cytotoxicity assay. CTX-TNA2 and U87-MG cells were cultured with different concentrations (100 and 200 μg/ml) of various types of RMSNs for 4 and 24 h under 10% serum-containing media condition. Cell viability was detected with an MTT assay.
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