ZFIN Image: Gabryelska et al., 2022, Fig. 4

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Figure Caption

Fig. 4

Homodimerization of U8 snoRNA and U2 snRNA. (A) Distribution of overlapping chimeras along the TMEM107 gene in PARIS (HEK293 cells) (Lu et al. 2016). All overlapping chimeras coincide with the position of U8 snoRNA in the 3′ UTR of TMEM107 transcript. (B, left) Coverage map of U8:U8 chimeras. Numbers on the x- and y-axes indicate positions in the TMEM107 transcript. The position of mature U8 snoRNA is indicated by the gray bars. (Middle) Mapping positions of both arms of chimeras along TMEM107. Some chimeras extend beyond the 5′ end of mature U8 (gray bar), indicating that they originate from the U8 precursor molecule. (Right) Predicted base-pairing of U8:U8 homdimer. (C) As above, analysis of U2:U2 chimeras. Coordinates indicate positions along the U2 transcript.

Acknowledgments

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