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Fig. 5
Inhibition of protein translation occurred during the angiogenic switch. a The volcano plot of the gene expression change of the dissected transplant microtumors transcriptome during the angiogenic switch (n = 3). b-d The GSEA analysis of transcriptome for the cytoplasmic translation, translational elongation and translational termination gene sets (n = 3). e The GSEA analysis of transcriptome for the significantly changed pathways during the angiogenic switch (n = 3). f The GSEA analysis of transcriptome for the aminoacyl-trans biosynthesis pathway during the angiogenic switch (n = 3). g-i The change of FPKM of RNAseq data for some aminoacyl-tRNA synthetases of the aminoacyl-trans biosynthesis during the angiogenic switch. Unpaired t-test, *P < 0.05, ** P < 0.01 (n = 3)