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Fig. 2 - supplement 1

ID: ZDB-IMAGE-220617-4
Publication: Lai et al., 2022 - DNA-damage induced cell death in yap1;wwtr1 mutant epidermal basal cells
All Figures: Figures for Lai et al., 2022

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Figure Caption

Fig. 2 - supplement 1

Yap1 and Wwtr1 are localized to the nuclei of epidermal basal cells (EBCs), and Yap1’s Tead-binding domain is essential in EBC survival.

(Top) Schematic of the encoded protein product of the zebrafish yap1 WT and bns22 alleles. S54 is necessary for Yap1 binding to Teads. (Bottom) Maximum intensity projections of 16–18 ss WT and yap1^bns22/bns22;wwtr1^-/- embryos stained with TUNEL and P63. Scale bars, 100 µm.

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