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Publication: Tchivelekete et al., 2022 - Evaluation of okadaic acid toxicity in human retinal cells and zebrafish retinas
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Fig. 1

Fig. 1. OA induced effects on ROS production, CAT activity and the level of MDA as well as GSH. (A) ROS production was significantly increased in ARPE-19 cells exposed to OA compared to the untreated control group. CAT activity was significantly decreased in ARPE-19 cells treated with OA for 24 h. GSH level was markedly decreased, and MDA production was significantly increased in ARPE-19 cells treated with OA for 24 h. (B) ARPE-19 cells exposed to OA for 24 h had a significant decrease in antioxidant gene expression measured by qRT-PCR and normalized to the housekeeping gene, GAPDH. Data was presented as mean ± SEM (n = 6). *p < 0.05; * *p < 0.01; * **p < 0.001; * ** *p < 0.0001.

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