ZFIN Image: Tchivelekete et al., 2022, Fig. 1

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Fig. 1

Fig. 1. OA induced effects on ROS production, CAT activity and the level of MDA as well as GSH. (A) ROS production was significantly increased in ARPE-19 cells exposed to OA compared to the untreated control group. CAT activity was significantly decreased in ARPE-19 cells treated with OA for 24?h. GSH level was markedly decreased, and MDA production was significantly increased in ARPE-19 cells treated with OA for 24?h. (B) ARPE-19 cells exposed to OA for 24?h had a significant decrease in antioxidant gene expression measured by qRT-PCR and normalized to the housekeeping gene, GAPDH. Data was presented as mean ±?SEM (n?=?6). *p?<?0.05; *?*p?<?0.01; *?**p?<?0.001; *?**?*p?<?0.0001.

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