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Fig. 4 PPARγ modulation decreases islet area. Islet areas were approximated by quantifying the β cell area in 4 dpf Tg(insulin-GFP) transgenic zebrafish. At the highest exposure concentration (10 μM), both antagonist and agonist exposure significantly decreased islet area. Boxplots are shown to indicate data quartiles, and p-values are shown comparing the control and 10 μM groups above the plots. n = 36–42 antagonist; n = 30–40 agonist eleutheroembryos.
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Full text @ Tox. App. Pharmacol.