IMAGE

Figure 4—figure supplement 1.

ID: ZDB-IMAGE-220416-98
Publication: Yang et al., 2022 - Innervation modulates the functional connectivity between pancreatic endocrine cells
All Figures: Figures for Yang et al., 2022

Image

Figure Caption

Figure 4—figure supplement 1. Targeted ablation of peri-islet neurons affects islet nerve density and islet cell activity.

(A) 100 hpf Et(1121A:GAL4FF); Tg(UAS:GCaMP6s) zebrafish immuno-stained for acetylated Tubulin (nerves) and counterstained with DAPI (DNA). (B) Islet nerve density is quantified following ablation of peri-islet neurons; mean ± standard error of the mean (SEM), n = 7 animals, p value from t-test. (C) Average homotypic (delta–delta and alpha–alpha) and heterotypic (delta–beta and alpha–delta) cell correlation coefficients with cell distance distribution from 1 (close) to 10 (far), mean ± SEM and linear regression (solid lines) with 95% confidence intervals; n = 11–12 animals, p values of slope and intercept from simple linear regression.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife