ZFIN Image: Vasileva et al., 2022, Figure 7

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Figure Caption

Figure 7

Surfen inhibits EWSR1-FLI1-mediated growth in the zebrafish model.

(A) Surfen inhibits the development of EWSR1-FLI1-driven outgrowths in zebrafish larvae. (B) Surfen inhibits progression of EWSR1-FLI1-driven tumors. Animals with eGFP-positive tumors were grouped for treatment with surfen (N = 4) or DMSO (N = 4). Each group had tumors similar in size and location. (C) Quantification of changes in tumor size based on fluorescence intensity. Error bars represent SD, **p < 0.01 based on two-way analysis of variance (ANOVA) test.

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