ZFIN Image: Vasileva et al., 2022, Figure 5.

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Figure Caption

Figure 5. Liquid chromatography–mass spectrometry (LC–MS/MS) analysis of proteins affected by <italic toggle='yes'>EWSR1-FLI1</italic> expression in developing zebrafish.

(A) Heat map representing the differentially expressed proteins dysregulated by EWSR1-FLI1 at 24 and 48 hpf. (B) Quantitative analysis of the differentially expressed proteins at 24 and 48 hpf. (C, D) Gene ontology (GO) analysis of differentially expressed proteins at 48 hpf. (E) Volcano plot of significantly downregulated and upregulated proteins in EWSR1-FLI1-expressing embryos. (F) Heatmap of the most differentially expressed proteins involved in proteoglycan metabolism in human Ewing sarcoma compared to normal tissue (GSE17674).

Acknowledgments

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