ZFIN Image: Wohlfart et al., 2022, Fig. 5

Image

Figure Caption

Fig. 5

aldh2.1^−/−mutants exhibited aggravated stress-signaling and an impairment of glycolysis and gluconeogenesis. A: Bar diagram for highest, significantly increased or decreased pathways in a Kyoto-encyclopedia of gene and genomes (KEGG) pathways analysis in aldh2.1^−/− larvae. B-E: Gene set enrichment analysis (GSEA) plots for VEGF (B), MAPK (C), glycolysis/gluconeogenesis (D), pyruvate metabolism (E) pathways. RNA-seq was done with mRNA in 120 hpf zebrafish larvae, quantification via normalized enrichment score (NES), n = 5 clutches, 50 larvae per clutch, ns = not significant, *p < 0.05, **p < 0.01, ***p < 0.001.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Redox Biol.