Fig. 8
Inhibition of p38 MAPK caused angiogenic alterations in hyaloid vasculature in aldh2.1+/+larvae. A) Representative confocal images of hyaloid vasculature in zebrafish larvae at 120 hpf with and without MAPK inhibitor treatment. Red scale bar: 20 μm. B) Quantification of larval hyaloid vasculature showed increased amount of branch points in aldh2.1+/+ larvae with MAPK inhibitor comparable to aldh2.1−/− mutants, n = 23–28 eyes per group. Statistical analysis was done via Student's t-test, ns = not significant, *p < 0.05. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)