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FIGURE 12 Hypothetical model on roles of EGFR signaling in controlling folliculogenesis in zebrafish. (A) Intrafollicular distribution of EGF family ligands and their receptor EGFR (Egfra) in the follicle (Tse and Ge, 2010), suggesting an oocyte-to-follicle cell signaling pathway. (B) EGF ligands-EGFR signaling pathway plays an important role in controlling early follicle development in zebrafish especially follicle activation or PG-PV transition.
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Full text @ Front Cell Dev Biol