ZFIN Image: Dadras et al., 2021, Fig. 8

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Figure Caption

Fig. 8

Enriched Par3-positive cells in GBM tumor tissue with stem-like cell populations.

a Representative images displaying staining of Par3, NESTIN, CD133, SOX2, GFAP, and GLAST-1, in normal brain and GBM samples. Brown pseudo-color is shown on the left and original fluorescence color to the right. Magnification bars, 100 µm. b Par3 expression in normal, GBM, and anaplastic astrocytoma samples (color-coded) plotted in relation to the five marker proteins in the same tissue. Tumor cells were divided in two groups, GBM_Diff (SOX2^low/NESTIN^low/CD133^low/GLAST-1^high/GFAP^high), shown in the figure as SOX2^L/NESTIN^L/CD133^L/GLAST-1^H/GFAP^H and GBM_Stem-Like (SOX2^high/NESTIN^high/CD133^high/GLAST-1^low/GFAP^low) shown in the figure as SOX2^H/NESTIN^H/CD133^H/GLAST-1^L/GFAP^L. Significant differences, *p < 0.05; ****p < 0.0001; n.s. not-significant.

Acknowledgments

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