ZFIN Image: Sveinsdóttir et al., 2022, Fig 4

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Figure Caption

Fig 4

Radar chart for sleep parameters of dopamine agonist or precursor treated vmat2 larvae at night and day.

Homozygous vmat2 (HOM) larvae were either left untreated (naïve, grey colour) or treated with three different concentrations (1μM, light green colour; 10μM, green colour; and 100μM, dark green colour) of pramipexole or L-Dopa and sleep parameters were analysed. Pramipexole did not significantly alter any sleep parameters while L-Dopa significantly altered the sleep dynamics at multiple parameters in dose dependent manner during the night (A-B) whereas during the day both compounds had immense dose-depended effects on all parameters (C-D). Data are represented as fold change of untreated wild type (naïve, black colour) larvae. For values and statistics see Table 3.

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Acknowledgments

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