IMAGE

Fig. 2

ID
ZDB-IMAGE-220113-2
Publication
Mullapudi et al., 2019 - Disruption of the pancreatic vasculature in zebrafish affects islet architecture and function
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Figures for Mullapudi et al., 2019
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Figure Caption

Fig. 2 dnVegfaa exerts a dose-dependent effect on β-cell dispersion. (A) β-Cells (green) from 48 hpf Tg(ins:GFP) embryos with mosaic Tg(ins:dnvegfaa) expression. The percentage of β-cells expressing dnvegfaa (magenta) is indicated, as is the severity of islet dispersion (intact, moderate or severe; white). (B) Quantification of embryos displaying varying severity of islet dispersion. (C-J) Immunostaining for insulin (β-cells, red) and endothelial cells (green) in 48 hpf Tg(fli:GFP) embryos, in combination with the indicated transgenic or mutant line, n=3-5 animals per genotype. Maximum intensity projections are presented. A, anterior; D, dorsal.

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