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Figure 5
The identification of brain development-related genes was downregulated, but suppressed in the p53 mutant lines with Bad knockdown. (A) Identification of downstream brain development-related genes such as crybb1, pvalb5, irx4a, pax7a, and fabp7a in wild-type zebrafish by qRT-PCR at 24 hpf. All data were analyzed using either paired or unpaired Student’s t-tests, as appropriate. * p < 0.01. (B) Enhanced brain-development genes crybb1, pvalb5, irx4a, pax7a, and fabp7a in p53 mutant lines during Bad knockdown at 24 hpf, as shown by qRT-PCR. All data were analyzed using either paired or unpaired Student’s t-tests, as appropriate. * p < 0.01.