Image
|
Figure Caption
Figure 9
Our proposed model of regeneration during chronic hyperglycemia versus regeneration upon acute injury. Following acute injury, activated Müller glia divide to produce multipotent progenitors that can give rise to all neuronal cell types. Under conditions of chronic hyperglycemia, lost photoreceptors are replenished through neurod-expressing progenitors that likely arise in the INL. Unlike the classically described “rod progenitors”, these proliferative progenitors give rise to both rods and cones.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Cells