ZFIN Image: Schnur et al., 2021, Figure 3:

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Figure Caption

Figure 3:

Fig. 3. Severe dysmorphic features in embryonic uba2^-/- zebrafish.

(a, b) Dorsal and lateral views of uba2 zebrafish at 8 dpf. Compared to wild-type (WT) controls, mutant lines showed aberrant head development with small eyes and hydrocephalus. (c) Bar graph representing the percentage of uba2^-/- zebrafish with gross morphological defects. (d) Survival curve showing the number of live fish over the course of 21 days. WT and heterozygous fish showed similar death curves, but homozygous fish had steeper death curves with 100% mortality by day 12. B brain, F craniofacial, PF pectoral fins, SB swim bladder, T tail.

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Acknowledgments

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