ZFIN Image: Zhang et al., 2021, FIGURE 4

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FIGURE 4

Figure 4. Impaired proliferation of exocrine pancreas progenitors and HSPCs in ltv1^?14/?14 mutant. (A,B) Representative confocal images of pH3 immunostaining (A) or BrdU labeling (B) in ltv1^?14/?14; ptf1a:gfp mutants and siblings at 2 dpf. (A?,B?) The percentage of pH3⁺ (A?, siblings, N = 6; mutants, N = 9) or BrdU⁺ (B?, siblings, N = 6; mutants, N = 6) cells within the ptf1a⁺ population in ltv1^?14/?14 mutants and siblings at 2 dpf. Bars represent means with SD. (C,D) Representative confocal images of pH3 immunostaining (C) and BrdU labeling (D) in ltv1^?14/?14; runx1:en-gfp mutants and siblings at 2.5 dpf. (C?,D?) The percentage of pH3⁺ (C?, siblings, N = 6; mutants, N = 7) and BrdU⁺ (D?, siblings, N = 6; mutants, N = 11) cells within the runx1⁺ population in ltv1^?14/?14 mutants and siblings at 2.5 dpf. Bars represent means with SD. White arrow: merged cell. Scale bar: 10 ?m.

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Acknowledgments

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