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Fig 7
A Protein-protein interaction network from the 130 most abundant proteins in D436H mutant when challenged with 59 ?g/mL norvaline for 12 hours. 942 PPIs identified with PPI enrichment p-value < 1.0x10-16. B PPI network from 130 randomly selected proteins in D436H mutant when challenged with 59 ?g/mL norvaline for 12 hours. 102 PPIs identified with PPI enrichment p-value of 0.0397. C Clp protease/chaperonin family local network cluster identified in a (false discovery rate: 0.00072). D Temporal signature of the heat shock response. Protein expression levels of D436H norvaline relative to WT norvaline were measured by spectral counting.